Infusion Therapy For Chronic Gout

Content

• Treatment: Uric Acid Lowering Therapy
• Prescription Medicines
• Typical Presentation Of Gout
• Gout Prevention
• What Are Symptoms Of Gout?

With time, attacks of gouty arthritis can occur more frequently and may last longer. While the first attacks usually involve only one or two joints, multiple joints can be involved simultaneously over time. It is important to note that unrecognizable , potentially damaging inflammation in joints can occur between attacks of obvious flares of gouty arthritis.

Treatment: Uric Acid Lowering Therapy

Xanthine oxidase inhibitors like allopurinol reduce the amount of uric acid produced by the body. Red meat and organ meats, such as liver, are especially high in purines. Purine-rich seafood includes anchovies, sardines, mussels, scallops, trout and tuna. Low-fat dairy products may be a better source of protein for people prone to gout. This test uses sound waves to detect urate crystals in joints or in tophi.

During an attack, rest the affected joint and apply ice packs or cold compresses to that spot. Probenecid is a medicine that works for people who cannot get rid of enough uric acid. Probenecid is not safe to take for many people with kidney disease, so talk to your doctor for more information about probenecid. Taking NSAIDs can lead to kidney disease over time or make kidney disease worse. NSAIDs may not be recommended when you have kidney disease even for the treatment of gout attacks. If a patient can’t tolerate allopurinol, and meets the criteria for probenecid, that can be tried.

Prescription Medicines

Fever — In some cases, gout symptoms are accompanied with fever. Wikipedia's health care articles can be viewed offline with the Medical Wikipedia app. Colchicine is an alternative for those unable to tolerate NSAIDs. At lower doses, which are still effective, it is well tolerated. Colchicine may interact with other commonly prescribed drugs, such as atorvastatin and erythromycin, among others.

Typical Presentation Of Gout

Rest the affected joint until the attack eases and for 24 hours after the attack. Your doctor may evaluate you for lead poisoning if you have been exposed to lead in your job or through hobbies. A diet rich in meat and seafood, which can be high in purines.

Patients should be instructed to go on a diet if obese, to stop drinking beer, and to avoid purine-rich foods. Dosages of colchicine did not have to be adjusted when the drug was used in combination with azithromycin. Rather, foods high in purines can increase the risk of gout, particularly in someone who is secreting too little uric acid. These include seafoods such as mussels, lobster, sardines and salmon, as well as beer, bacon, liver, sweetbreads, turkey, veal, and high fructose corn syrup. High fructose corn syrup is often found in processed foods such as soft drinks, chips and biscuits, syrups, chutneys and sauces.

Pegloticase is given as an intravenous infusion every two weeks, and reduces uric acid levels. Pegloticase is useful decreasing tophi but has a high rate of side effects and many people develop resistance to it. Potential side effects include kidney stones, anemia and joint pain.

There are also some things you can do at home to relieve symptoms. Gout is caused by monosodium urate crystal deposits in the joints. It may also be caused by eating a lot of foods that are high in purines. You canlower uric acid levels by limiting foods high in purines, and alcohol intake .

Surgical Treatment

Some foods like red meat, alcohol, and high-fructose corn syrup in sodas can raise your risks. Limiting foods that cause gout in your diet can protect you from this painful joint condition, a type of arthritis. Doctors place gout under the umbrella term “arthritis” — a broad range of joint diseases and joint pain.

This generally can be avoided with the co-administration of prophylactic medications along with the uric acid lowering therapy. Pegloticase is an infusion medicine given by injection into your vein at your doctor’s office, usually every two weeks. It is used for severe chronic gout when other medicines do not work.